Osteopontin splice variants expressed by breast tumors regulate monocyte activation via MCP-1 and TGF-β1

Osteopontin (OPN), a multifunctional glycoprotein, has three transcripts that have distinct roles in tumors in vitro. Whether OPN transcripts have different functions in tumor processes in vivo is unclear. It has been reported that immune cell-derived OPN can promote tumor formation. We propose a hy...

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Detalhes bibliográficos
Main Authors: Sun, Jintang, Feng, Alei, Chen, Songyu, Zhang, Yun, Xie, Qi, Yang, Meixiang, Shao, Qianqian, Liu, Jia, Yang, Qifeng, Kong, Beihua, Qu, Xun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003052/
https://ncbi.nlm.nih.gov/pubmed/23416968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.67
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