Blocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient mice

AIM: Toll-like receptor 2 (TLR2) signaling plays a critical role in the initiation of atherosclerosis. The aim of this study was to investigate whether blocking TLR2 activity could produce therapeutic effects on advanced atherosclerosis. METHODS: Forty-week old apolipoprotein E-deficient (ApoE(−/−))...

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Autores principales: Wang, Xiao-xing, Lv, Xiao-xi, Wang, Jia-ping, Yan, Hui-min, Wang, Zi-yan, Liu, Han-zhi, Fu, Xiao-ming, Hu, Zhuo-wei
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003031/
https://ncbi.nlm.nih.gov/pubmed/23852085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.75
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