Blocking TLR2 activity attenuates pulmonary metastases of tumor.

BACKGROUND: Metastasis is the most pivotal cause of mortality in cancer patients. Immune tolerance plays a crucial role in tumor progression and metastasis. METHODS AND FINDINGS: In this study, we investigated the potential roles and mechanisms of TLR2 signaling on tumor metastasis in a mouse model...

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Main Authors: Hong-Zhen Yang, Bing Cui, Han-Zhi Liu, Su Mi, Jun Yan, Hui-Min Yan, Fang Hua, Heng Lin, Wen-Feng Cai, Wen-Jie Xie, Xiao-Xi Lv, Xiao-Xing Wang, Bing-Mu Xin, Qi-Min Zhan, Zhuo-Wei Hu
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2009-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC2716531?pdf=render
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