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Humanized mice are susceptible to Salmonella typhi infection

Salmonella enterica serovar Typhi is a pathogen that only infects humans. Currently, there is no animal model for studying this pathogen. Recently, alymphoid RAG-2(−/−)/γ(c)(−/−) mice engrafted with human leukocytes, known as humanized mice, have been successfully utilized to develop experimental mo...

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Detalhes bibliográficos
Main Authors: Firoz Mian, M, Pek, Elisabeth A, Chenoweth, Meghan J, Ashkar, Ali A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002987/
https://ncbi.nlm.nih.gov/pubmed/21200387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.52
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