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Bicyclol protects HepG2 cells against D-galactosamine-induced apoptosis through inducing heat shock protein 27 and mitochondria associated pathway

AIM: To study the inducing effect of bicyclol on heat shock protein 27 (HSP27) and its role on anti-apoptosis in HepG2 cells intoxicated with D-galactosamine (D-GaIN). METHODS: HepG2 cells were treated with various concentrations of bicyclol and then subjected to D-GaIN intoxication. Apoptosis was a...

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Autors principals: Bao, Xiu-qi, Liu, Geng-tao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002839/
https://ncbi.nlm.nih.gov/pubmed/20139905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.194
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