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Peli: a family of signal-responsive E3 ubiquitin ligases mediating TLR signaling and T-cell tolerance

E3 ubiquitin ligases play a crucial role in regulating immune receptor signaling and modulating immune homeostasis and activation. One emerging family of such E3s is the Pelle-interacting (Peli) proteins, characterized by the presence of a cryptic forkhead-associated domain involved in substrate bin...

詳細記述

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書誌詳細
主要な著者: Jin, Wei, Chang, Mikyoung, Sun, Shao-Cong
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002811/
https://ncbi.nlm.nih.gov/pubmed/22307041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.60
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