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Electrophysiological mechanisms of sophocarpine as a potential antiarrhythmic agent

AIM: To examine the electrophysiological effects of sophocarpine on action potentials (AP) and ionic currents of cardiac myocytes and to compare some of these effects with those of amiodarone. METHODS: Langendorff perfusion set-up was used in isolated guinea pig heart, and responses to sophocarpine...

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Détails bibliographiques
Auteurs principaux: Yang, Zhi-fang, Li, Ci-zhen, Wang, Wei, Chen, Ying-min, Zhang, Ying, Liu, Yuan-mou, Wang, Hong-wei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002765/
https://ncbi.nlm.nih.gov/pubmed/21258356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.207
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