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Electrophysiological mechanism for the antiarrhythmic action of propafenone: a comparison with mexiletine.

1. The antiarrhythmic potency of propafenone was evaluated in the guinea-pig isolated heart; arrhythmias were induced with (a) digitalis intoxication and (b) hypoxia followed by reoxygenation. 2. Propafenone, 0.5 microM, was found to be the minimal but effective antiarrhythmic concentration. The ant...

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Bibliografski detalji
Glavni autori: Amerini, S., Bernabei, R., Carbonin, P., Cerbai, E., Mugelli, A., Pahor, M.
Format: Artigo
Jezik:Inglês
Izdano: 1988
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854270/
https://ncbi.nlm.nih.gov/pubmed/3219479
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