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Effect of prototypical inducers on ligand activated nuclear receptor regulated drug disposition genes in rodent hepatic and intestinal cells

AIM: The aim of this study was to investigate the impact on expression of mRNA and protein by paradigm inducers/activators of nuclear receptors and their target genes in rat hepatic and intestinal cells. Furthermore, assess marked inter laboratory conflicting reports regarding species and tissue dif...

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Detalhes bibliográficos
Main Authors: Martin, Philip, Riley, Robert, Thompson, Paul, Williams, Dominic, Back, David, Owen, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002700/
https://ncbi.nlm.nih.gov/pubmed/20048746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.187
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