Enhancing the potency of lithospermate B for inhibiting Na(+)/K(+)-ATPase activity by forming transition metal ion complexes

AIM: To determine whether replacing Mg(2+) in magnesium lithospermate B (Mg-LSB) isolated from danshen (Salvia miltiorrhiza) with other metal ions could affect its potency in inhibition of Na(+)/K(+)-ATPase activity. METHODS: Eight metal ions (Na(+), K(+), Mg(2+), Cr(3+), Mn(2+), Co(2+), Ni(2+), and...

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Bibliographische Detailangaben
Hauptverfasser: Lin, Nan-Hei, Chung, Tse-Yu, Li, Feng-Yin, Chen, Hsin-An, Tzen, Jason TC
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002613/
https://ncbi.nlm.nih.gov/pubmed/23685954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2013.32
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