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Magnesium lithospermate B extracted from Salvia miltiorrhiza elevats intracellular Ca(2+) level in SH-SY5Y cells

AIM: To examine if magnesium lithospermate B (MLB), a potent inhibitor of Na(+)/K(+)-ATPase, leads to the elevation of intracellular Ca(2+) level as observed in cells treated with cardiac glycosides. METHODS: Viability of SH-SY5Y neuroblastoma cells treated with various concentrations of ouabain or...

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Detalhes bibliográficos
Main Authors: Chen, Yi-ching, Jinn, Tzyy-rong, Chung, Tse-yu, Li, Feng-yin, Fan, Ruey-jane, Tzen, Jason TC
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007822/
https://ncbi.nlm.nih.gov/pubmed/20686517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.102
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