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Norisoboldine alleviates joint destruction in rats with adjuvant-induced arthritis by reducing RANKL, IL-6, PGE(2), and MMP-13 expression
AIM: To explore the effects of norisoboldine (NOR), a major isoquinoline alkaloid in Radix Linderae, on joint destruction in rats with adjuvant-induced arthritis (AIA) and its underlying mechanisms. METHODS: AIA was induced in adult male SD rats by intradermal injection of Mycobacterium butyricum in...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002497/ https://ncbi.nlm.nih.gov/pubmed/23396374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.187 |
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