Co-delivery of ccl19 gene enhances anti-caries DNA vaccine pCIA-P immunogenicity in mice by increasing dendritic cell migration to secondary lymphoid tissues

AIM: To investigate how co-delivery of the gene encoding C–C chemokine ligand-19 (CCL-19) affected the systemic immune responses to an anti-caries DNA vaccine pCIA-P in mice. METHODS: Plasmid encoding CCL19-GFP fusion protein (pCCL19/GFP) was constructed by inserting murine ccl19 gene into GFP-expre...

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Bibliografiska uppgifter
Huvudupphovsmän: Yan, Yan-hong, Qi, Sheng-cai, Su, Ling-kai, Xu, Qing-an, Fan, Ming-wen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2013
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002487/
https://ncbi.nlm.nih.gov/pubmed/23334235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.153
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