Proteomic analysis of the effect of iptakalim on human pulmonary arterial smooth muscle cell proliferation

AIM: To investigate the anti-proliferative effect of iptakalim (Ipt), a newly selective K(ATP) channel opener, in endothelin-1 (ET-1)-induced human pulmonary arterial smooth muscle cells (PASMCs) using proteomic analysis. METHODS: Human PASMCs were incubated with ET-1 (10(−8) mol/L) and ET-1 (10(−8)...

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Autori principali: Yang, Ming-xia, Liu, Zheng-xia, Zhang, Shu, Jing, Yu, Zhang, Shi-jiang, Xie, Wei-ping, Ma, Lei, Zhu, Chang-liang, Wang, Hong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002473/
https://ncbi.nlm.nih.gov/pubmed/19169269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2008.30
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