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Effect of Needle Insertion Speed on Tissue Injury, Stress, and Backflow Distribution for Convection-Enhanced Delivery in the Rat Brain
Flow back along a needle track (backflow) can be a problem during direct infusion, e.g. convection-enhanced delivery (CED), of drugs into soft tissues such as brain. In this study, the effect of needle insertion speed on local tissue injury and backflow was evaluated in vivo in the rat brain. Needle...
সংরক্ষণ করুন:
প্রধান লেখক: | , , |
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বিন্যাস: | Artigo |
ভাষা: | Inglês |
প্রকাশিত: |
Public Library of Science
2014
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বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002424/ https://ncbi.nlm.nih.gov/pubmed/24776986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094919 |
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