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A mutant of HBx (HBxΔ127) promotes hepatoma cell growth via sterol regulatory element binding protein 1c involving 5-lipoxygenase

AIM: Previously, we identified a natural mutant of hepatitis B virus X gene (HBx) with a deletion from 382 to 401 base pairs (termed HBxΔ127), which could potently enhance growth of hepatoma cells. In this study, we further investigated the mechanism of increased hepatoma cell growth that was mediat...

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Detalhes bibliográficos
Main Authors: Wang, Qi, Zhang, Wei-ying, Ye, Li-hong, Zhang, Xiao-dong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002418/
https://ncbi.nlm.nih.gov/pubmed/20173757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.5
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