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The novel squamosamide derivative FLZ enhances BDNF/TrkB/CREB signaling and inhibits neuronal apoptosis in APP/PS1 mice

AIM: The aim of this study was to study the effects of compound FLZ, a novel cyclic derivative of squamosamide from Annona glabra, on brain-derived neurotrophic factor (BDNF)/tropomyosin receptor kinase B (TrkB)/cAMP response element-binding protein (CREB) signaling and neuronal apoptosis in the hip...

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Detalhes bibliográficos
Main Authors: Li, Ning, Liu, Geng-tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002416/
https://ncbi.nlm.nih.gov/pubmed/20154710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.3
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