Structural changes of tumor necrosis factor alpha associated with membrane insertion and channel formation.
Low pH enhances tumor necrosis factor alpha (TNF)-induced cytolysis of cancer cells and TNF-membrane interactions that include binding, insertion, and ion-channel formation. We have also found that TNF increases Na+ influx in cells. Here, we examined the structural features of the TNF-membrane inter...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40023/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8577707/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.3.1021 |
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