ACE2 deficiency increases NADPH‐mediated oxidative stress in the kidney

Angiotensin‐converting enzyme 2 (ACE2) is highly expressed in the kidney and hydrolyzes angiotensin II (Ang II) to Ang(1–7). Since Ang II is a strong activator of oxidative stress, we reasoned that ACE2 could be involved in the regulation of renal oxidative stress by governing the levels of Ang II....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wysocki, Jan, Ortiz‐Melo, David I., Mattocks, Natalie K., Xu, Katherine, Prescott, Jessica, Evora, Karla, Ye, Minghao, Sparks, Matthew A., Haque, Syed K., Batlle, Daniel, Gurley, Susan B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2014
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002244/
https://ncbi.nlm.nih.gov/pubmed/24760518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.264
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