ACE2 deficiency increases NADPH‐mediated oxidative stress in the kidney

Angiotensin‐converting enzyme 2 (ACE2) is highly expressed in the kidney and hydrolyzes angiotensin II (Ang II) to Ang(1–7). Since Ang II is a strong activator of oxidative stress, we reasoned that ACE2 could be involved in the regulation of renal oxidative stress by governing the levels of Ang II....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wysocki, Jan, Ortiz‐Melo, David I., Mattocks, Natalie K., Xu, Katherine, Prescott, Jessica, Evora, Karla, Ye, Minghao, Sparks, Matthew A., Haque, Syed K., Batlle, Daniel, Gurley, Susan B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002244/
https://ncbi.nlm.nih.gov/pubmed/24760518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.264
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados