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Parallel synthesis and splicing redirection activity of cell-penetrating peptide conjugate libraries of a PNA cargo

A novel method for the parallel synthesis of peptide-biocargo conjugates was developed that utilizes affinity purification for fast isolation of the conjugates in order to avoid time consuming HPLC purification. The methodology was applied to create two libraries of cell-penetrating peptide (CPP)–PN...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Deuss, Peter J., Arzumanov, Andrey A., Williams, Donna L., Gait, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002126/
https://ncbi.nlm.nih.gov/pubmed/24105028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob41659c
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