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Differential Transmembrane Domain GXXXG Motif Pairing Impacts Major Histocompatibility Complex (MHC) Class II Structure

Major histocompatibility complex (MHC) class II molecules exhibit conformational heterogeneity, which influences their ability to stimulate CD4 T cells and drive immune responses. Previous studies suggest a role for the transmembrane domain of the class II αβ heterodimer in determining molecular str...

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書誌詳細
主要な著者: Dixon, Ann M., Drake, Lisa, Hughes, Kelly T., Sargent, Elizabeth, Hunt, Danielle, Harton, Jonathan A., Drake, James R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002079/
https://ncbi.nlm.nih.gov/pubmed/24619409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.516997
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