Leishmania major inhibits IL-12 in macrophages by signaling through CR3 (CD11b/CD18) and downregulation of ETS-mediated transcription

Leishmania major is an etiological agent of cutaneous leishmaniasis. The parasite primarily infects immune sentinel cells, specifically macrophages and dendritic cells, in the mammalian host. Infection is receptor mediated and is known to involve parasite binding to cell surface protein complement r...

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Main Authors: Ricardo-Carter, Cristina, Favila, Michelle, Polando, Rachel E., Cotton, Rachel N., Horner, Kimberly Bogard, Condon, David, Ballhorn, Wibke, Whitcomb, James P., Yadav, Mahesh, Geister, Rebecca L., Schorey, Jeffery S., McDowell, Mary Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001918/
https://ncbi.nlm.nih.gov/pubmed/23834512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pim.12049
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