Catalytic activity of the mouse guanine nucleotide exchanger mSOS is activated by Fyn tyrosine protein kinase and the T-cell antigen receptor in T cells.

Eitemau Tebyg

• Mitogenic activation of the Ras guanine nucleotide exchange factor in NIH 3T3 cells involves protein tyrosine phosphorylation.
  gan: Li, B Q, et al.
  Cyhoeddwyd: (1993)
• The Ras-specific exchange factors mouse Sos1 (mSos1) and mSos2 are regulated differently: mSos2 contains ubiquitination signals absent in mSos1.
  gan: Nielsen, K H, et al.
  Cyhoeddwyd: (1997)
• Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.
  gan: Quilliam, L A, et al.
  Cyhoeddwyd: (1994)
• cAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor.
  gan: Burgering, B M, et al.
  Cyhoeddwyd: (1993)
• Ras-Guanine Nucleotide Exchange Factor Sos2 Is Dispensable for Mouse Growth and Development
  gan: Esteban, Luis M., et al.
  Cyhoeddwyd: (2000)