A single-dose toxicity study on non-radioactive iodinated hypericin for a targeted anticancer therapy in mice

AIM: Hypericin (Hyp) and its radio-derivatives have been investigated in animal models with ischemic heart diseases and malignancies for diagnostic and therapeutic purposes. Before radioiodinated Hyp ((123)I-Hyp or (131)I-Hyp) can be considered as a clinically useful drug, vigorous evaluations on it...

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Bibliografski detalji
Glavni autori: Li, Jun-jie, Cona, Marlein Miranda, Feng, Yuan-bo, Chen, Feng, Zhang, Guo-zhi, Fu, Xue-bin, Himmelreich, Uwe, Oyen, Raymond, Verbruggen, Alfons, Ni, Yi-cheng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001835/
https://ncbi.nlm.nih.gov/pubmed/23103619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.111
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