Diverse Responses to Vascular Disrupting Agent Combretastatin A4 Phosphate: A Comparative Study in Rats with Hepatic and Subcutaneous Tumor Allografts Using MRI Biomarkers, Microangiography, and Histopathology

OBJECTIVE: Differently located tumors of the same origin may exhibit diverse responses to the same therapeutics. To test this hypothesis, we compared the responses of rodent hepatic and subcutaneous engrafts of rhabdomyosarcoma-1 (R1) to a vascular disrupting agent Combretastatin A4 phosphate (CA4P)...

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Bibliographic Details
Main Authors: Li, Junjie, Chen, Feng, Feng, Yuanbo, Cona, Marlein Miranda, Yu, Jie, Verbruggen, Alfons, Zhang, Jian, Oyen, Raymond, Ni, Yicheng
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2013
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573653/
https://ncbi.nlm.nih.gov/pubmed/23418616
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