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Diverse Responses to Vascular Disrupting Agent Combretastatin A4 Phosphate: A Comparative Study in Rats with Hepatic and Subcutaneous Tumor Allografts Using MRI Biomarkers, Microangiography, and Histopathology

OBJECTIVE: Differently located tumors of the same origin may exhibit diverse responses to the same therapeutics. To test this hypothesis, we compared the responses of rodent hepatic and subcutaneous engrafts of rhabdomyosarcoma-1 (R1) to a vascular disrupting agent Combretastatin A4 phosphate (CA4P)...

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Detalhes bibliográficos
Main Authors: Li, Junjie, Chen, Feng, Feng, Yuanbo, Cona, Marlein Miranda, Yu, Jie, Verbruggen, Alfons, Zhang, Jian, Oyen, Raymond, Ni, Yicheng
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573653/
https://ncbi.nlm.nih.gov/pubmed/23418616
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