A Statin-Loaded Reconstituted High-Density Lipoprotein Nanoparticle Inhibits Atherosclerotic Plaque Inflammation

Inflammation is a key feature of atherosclerosis and a target for therapy. Statins have potent anti-inflammatory properties but these cannot be fully exploited with oral statin therapy due to low systemic bioavailability. Here we present an injectable reconstituted high-density lipoprotein (rHDL) na...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Duivenvoorden, Raphaël, Tang, Jun, Cormode, David P., Mieszawska, Aneta J., Izquierdo-Garcia, David, Ozcan, Canturk, Otten, Maarten J., Zaidi, Neeha, Lobatto, Mark E., van Rijs, Sarian M., Priem, Bram, Kuan, Emma L., Martel, Catherine, Hewing, Bernd, Sager, Hendrik, Nahrendorf, Matthias, Randolph, Gwendalyn J., Stroes, Erik S.G., Fuster, Valentin, Fisher, Edward A., Fayad, Zahi A., Mulder, Willem J.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001802/
https://ncbi.nlm.nih.gov/pubmed/24445279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4065
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi