Trichloroethylene Disrupts Cardiac Gene Expression and Calcium Homeostasis in Rat Myocytes

BACKGROUND: We have been investigating the molecular mechanisms by which trichloroethylene (TCE) might induce cardiac malformations in the embryonic heart. Previous investigations indicated that TCE disrupted expression of genes encoding proteins involved in regulation of intracellular Ca(2+), [Ca(2...

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Main Authors: Caldwell, Patricia T, Thorne, Patricia A, Boitano, Scott, Runyan, Raymond B, Johnson, Paula D, Selmin, Ornella
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001797/
https://ncbi.nlm.nih.gov/pubmed/18411232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn078
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