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Remodeling Promotes Proarrhythmic Disruption of Calcium Homeostasis in Failing Atrial Myocytes

It is well known that heart failure (HF) typically coexists with atrial fibrillation (AF). However, until now, no clear mechanism has been established that relates HF to AF. In this study, we apply a multiscale computational framework to establish a mechanistic link between atrial myocyte structural...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Shiferaw, Yohannes, Aistrup, Gary L., Louch, William E., Wasserstrom, J.A.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6976802/
https://ncbi.nlm.nih.gov/pubmed/31889516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.012
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