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Measurement of constitutive MAPK and PI3K/AKT signaling activity in human cancer cell lines

The growth and survival of cancer cells is often driven by constitutive activity in the mitogen activated protein kinase (MAPK) and phospho-inositide 3-kinase (PI3K)/AKT signaling pathways. Activity in these signal transduction cascades is known to contribute to the uncontrolled growth and resistanc...

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Bibliografiske detaljer
Main Authors: Paraiso, Kim H.T., Van Der Kooi, Kaisa, Messina, Jane L., Smalley, Keiran S. M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001792/
https://ncbi.nlm.nih.gov/pubmed/21036250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381298-8.00027-7
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