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Variability in clinical phenotypes of heterozygous and homozygous cases of Parkin-related Parkinson’s disease

Parkin mutations are a common cause of early-onset Parkinson’s disease. To study the clinical features and treatment responses of patients with homozygous or heterozygous Parkin mutations, we performed a retrospective chart review in six early-onset parkinsonism patients with pathogenic Parkin mutat...

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Detalhes bibliográficos
Main Authors: Thompson, Amanda J., Scholz, Sonja W., Singleton, Andrew B., Hardwick, Angela, McFarland, Nikolaus R., Okun, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001762/
https://ncbi.nlm.nih.gov/pubmed/23767969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00207454.2013.810626
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