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Parkinson’s disease with Lewy bodies associated with a heterozygous PARKIN dosage mutation

BACKGROUND: PARKIN -related disease remains incompletely understood. First, the pathogenicity of heterozygous PARKIN mutations is unclear though some evidence supports causality. Second, unlike sporadic Parkinson’s disease (PD), Lewy bodies are present only in a minority of cases. Only one other het...

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Detalhes bibliográficos
Publicado no:Mov Disord
Main Authors: Sharp, Madeleine E, Marder, Karen S, Côté, Lucien, Clark, Lorraine N, Nichols, William C, Vonsattel, Jean-Paul, Alcalay, Roy N
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281030/
https://ncbi.nlm.nih.gov/pubmed/24375549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25792
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