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Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes
Hypertrophy is central to several heart diseases; however, not much is known about the role of glycosphingolipids (GSLs) in this phenotype. Since GSLs have been accorded several physiological functions, we sought to determine whether these compounds affect cardiac hypertrophy. By using a rat cardiom...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001711/ https://ncbi.nlm.nih.gov/pubmed/24658420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu020 |
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