Type 1 angiotensin receptors on macrophages ameliorate IL-1 receptor–mediated kidney fibrosis

In a wide array of kidney diseases, type 1 angiotensin (AT1) receptors are present on the immune cells that infiltrate the renal interstitium. Here, we examined the actions of AT1 receptors on macrophages in progressive renal fibrosis and found that macrophage-specific AT1 receptor deficiency exacer...

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Detalhes bibliográficos
Main Authors: Zhang, Jian-dong, Patel, Mehul B., Griffiths, Robert, Dolber, Paul C., Ruiz, Phillip, Sparks, Matthew A., Stegbauer, Johannes, Jin, Huixia, Gomez, Jose A., Buckley, Anne F., Lefler, William S., Chen, Daian, Crowley, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001526/
https://ncbi.nlm.nih.gov/pubmed/24743144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61368
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