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The pregnane xenobiotic receptor, a prominent liver factor, has actions in the midbrain for neurosteroid synthesis and behavioral/neural plasticity of female rats

A novel factor of interest for growth/plasticity in the brain is pregnane xenobiotic receptor (PXR). PXR is a liver factor known for its role in xenobiotic clearance and cholesterol metabolism. It is expressed in the brain, suggesting a potential role for plasticity, particularly involving cholester...

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Autors principals: Frye, Cheryl A., Koonce, Carolyn J., Walf, Alicia A.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001026/
https://ncbi.nlm.nih.gov/pubmed/24795576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsys.2014.00060
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