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Granzyme K synergistically potentiates LPS-induced cytokine responses in human monocytes

Granzymes are serine proteases released by cytotoxic lymphocytes to induce apoptosis in virus-infected cells and tumor cells. Evidence is emerging that granzymes also play a role in controlling inflammation. Granzyme serum levels are elevated in patients with autoimmune diseases and infections, incl...

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Bibliografske podrobnosti
Main Authors: Wensink, Annette C., Kemp, Vera, Fermie, Job, García Laorden, M. Isabel, van der Poll, Tom, Hack, C. Erik, Bovenschen, Niels
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000831/
https://ncbi.nlm.nih.gov/pubmed/24711407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1317347111
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