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Role of the Unfolded Protein Response in β Cell Compensation and Failure during Diabetes
Pancreatic β cell failure leads to diabetes development. During disease progression, β cells adapt their secretory capacity to compensate the elevated glycaemia and the peripheral insulin resistance. This compensatory mechanism involves a fine-tuned regulation to modulate the endoplasmic reticulum (...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Hindawi Publishing Corporation
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000654/ https://ncbi.nlm.nih.gov/pubmed/24812634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/795171 |
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