Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides: S1 specificity of ERAP1, ERAP2 and IRAP

ER aminopeptidase 1 (ERAP1), ER aminopeptidase 2 (ERAP2) and Insulin Regulated aminopeptidase (IRAP) are three homologous enzymes that play critical roles in the generation of antigenic peptides. These aminopeptidases excise amino acids from N-terminally extended precursors of antigenic peptides in...

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Bibliografiske detaljer
Main Authors: Zervoudi, Efthalia, Papakyriakou, Athanasios, Georgiadou, Dimitra, Evnouchidou, Irini, Gajda, Anna, Poreba, Marcin, Salvesen, Guy S., Drag, Marcin, Hattori, Akira, Swevers, Luc, Vourloumis, Dionisios, Stratikos, Efstratios
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000605/
https://ncbi.nlm.nih.gov/pubmed/21314638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20102049
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