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Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts

AIM: To investigate whether resveratrol (3,4,5-trihydroxy-trans-stilbene) inhibits collagen I synthesis induced by insulin growth factor-1 (IGF-1) in intestinal fibroblasts, and to explore the possible molecular mechanisms. METHODS: Male Sprague-Dawley rats were randomly divided into two groups: a c...

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Bibliografske podrobnosti
Main Authors: Li, Ping, Liang, Mei-Lan, Zhu, Ying, Gong, Yao-Yao, Wang, Yun, Heng, Ding, Lin, Lin
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Co., Limited 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000501/
https://ncbi.nlm.nih.gov/pubmed/24782617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i16.4648
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