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Tissue Inhibitor of Metalloproteinase-2 Suppresses Collagen Synthesis in Cultured Keloid Fibroblasts

BACKGROUND: Keloids are defined as a kind of dermal fibroproliferative disorder resulting from the accumulation of collagen. In the remodeling of extracellular matrix, the balance between matrix metalloproteinases (MMPs) and the tissue inhibitors of metalloproteinases (TIMPs) is as critical as the p...

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Bibliografske podrobnosti
izdano v:Plast Reconstr Surg Glob Open
Main Authors: Dohi, Teruyuki, Miyake, Koichi, Aoki, Masayo, Ogawa, Rei, Akaishi, Satoshi, Shimada, Takashi, Okada, Takashi, Hyakusoku, Hiko
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer Health 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4596445/
https://ncbi.nlm.nih.gov/pubmed/26495233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/GOX.0000000000000503
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