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A two-step hierarchical hypothesis set testing framework, with applications to gene expression data on ordered categories

BACKGROUND: In complex large-scale experiments, in addition to simultaneously considering a large number of features, multiple hypotheses are often being tested for each feature. This leads to a problem of multi-dimensional multiple testing. For example, in gene expression studies over ordered categ...

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Detalhes bibliográficos
Main Authors: Li, Yihan, Ghosh, Debashis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000433/
https://ncbi.nlm.nih.gov/pubmed/24731138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-108
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