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Latent class model with familial dependence to address heterogeneity in complex diseases: adapting the approach to family-based association studies
Clinical diagnoses of complex diseases may often encompass multiple genetically heterogeneous disorders. One way of dissecting this heterogeneity is to apply latent class (LC) analysis to measurements related to the diagnosis, such as detailed symptoms, to define more homogeneous disease sub-types,...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000257/ https://ncbi.nlm.nih.gov/pubmed/21308764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20566 |
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