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Symptom dimensions as alternative phenotypes to address genetic heterogeneity in schizophrenia and bipolar disorder
This study introduces a novel way to use the lifetime ratings of symptoms of psychosis, mania and depression in genetic linkage analysis of schizophrenia (SZ) and bipolar disorder (BP). It suggests using a latent class model developed for family data to define more homogeneous symptom subtypes that...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3476706/ https://ncbi.nlm.nih.gov/pubmed/22535187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.67 |
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