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Symptom dimensions as alternative phenotypes to address genetic heterogeneity in schizophrenia and bipolar disorder

This study introduces a novel way to use the lifetime ratings of symptoms of psychosis, mania and depression in genetic linkage analysis of schizophrenia (SZ) and bipolar disorder (BP). It suggests using a latent class model developed for family data to define more homogeneous symptom subtypes that...

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Bibliografski detalji
Glavni autori: Labbe, Aurélie, Bureau, Alexandre, Moreau, Isabel, Roy, Marc-André, Chagnon, Yvon, Maziade, Michel, Merette, Chantal
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3476706/
https://ncbi.nlm.nih.gov/pubmed/22535187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.67
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