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FROM MOLECULAR PHYLOGENY TOWARDS DIFFERENTIATING PHARMACOLOGY FOR NMDA RECEPTOR SUBTYPES

In order to decode the roles that N-methyl-D-aspartate (NMDA) receptors play in excitatory neurotransmission, synaptic plasticity, and neuropathologies, there is need for ligands that differ in their subtype selectivity. The conantokin family of Conus peptides is the only group of peptidic natural p...

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Detalhes bibliográficos
Main Authors: Platt, Randall J., Curtice, Kigen J., Twede, Vernon D., Watkins, Maren, Gruszczyński, Paweł, Bulaj, Grzegorz, Horvath, Martin P., Olivera, Baldomero M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000240/
https://ncbi.nlm.nih.gov/pubmed/24508768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2014.01.016
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