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FROM MOLECULAR PHYLOGENY TOWARDS DIFFERENTIATING PHARMACOLOGY FOR NMDA RECEPTOR SUBTYPES

In order to decode the roles that N-methyl-D-aspartate (NMDA) receptors play in excitatory neurotransmission, synaptic plasticity, and neuropathologies, there is need for ligands that differ in their subtype selectivity. The conantokin family of Conus peptides is the only group of peptidic natural p...

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Détails bibliographiques
Auteurs principaux: Platt, Randall J., Curtice, Kigen J., Twede, Vernon D., Watkins, Maren, Gruszczyński, Paweł, Bulaj, Grzegorz, Horvath, Martin P., Olivera, Baldomero M.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000240/
https://ncbi.nlm.nih.gov/pubmed/24508768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2014.01.016
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