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Interferon-γ Resets Muscle Cell Fate by Stimulating the Sequential Recruitment of JARID2 and PRC2 to Promoters To Repress Myogenesis

The inflammatory cytokine interferon-γ (IFN-γ) orchestrates a diverse array of fundamental physiological processes. IFN-γ and the class II transactivator (CIITA) play essential roles in inhibiting muscle development during the inflammatory response. Here, we describe the mechanism through which IFN-...

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Detalhes bibliográficos
Main Authors: Londhe, Priya, Davie, Judith K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000160/
https://ncbi.nlm.nih.gov/pubmed/24327761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004633
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