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Interferon-γ Resets Muscle Cell Fate by Stimulating the Sequential Recruitment of JARID2 and PRC2 to Promoters To Repress Myogenesis
The inflammatory cytokine interferon-γ (IFN-γ) orchestrates a diverse array of fundamental physiological processes. IFN-γ and the class II transactivator (CIITA) play essential roles in inhibiting muscle development during the inflammatory response. Here, we describe the mechanism through which IFN-...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4000160/ https://ncbi.nlm.nih.gov/pubmed/24327761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004633 |
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