Structure and computational analysis of a novel protein with metallopeptidase-like and circularly permuted winged-helix-turn-helix domains reveals a possible role in modified polysaccharide biosynthesis

BACKGROUND: CA_C2195 from Clostridium acetobutylicum is a protein of unknown function. Sequence analysis predicted that part of the protein contained a metallopeptidase-related domain. There are over 200 homologs of similar size in large sequence databases such as UniProt, with pairwise sequence ide...

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Bibliographic Details
Main Authors: Das, Debanu, Murzin, Alexey G, Rawlings, Neil D, Finn, Robert D, Coggill, Penelope, Bateman, Alex, Godzik, Adam, Aravind, L
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000134/
https://ncbi.nlm.nih.gov/pubmed/24646163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-75
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