Toll-like receptor 9 agonist enhances anti-tumor immunity and inhibits tumor-associated immunosuppressive cells numbers in a mouse cervical cancer model following recombinant lipoprotein therapy

BACKGROUND: Although cytotoxic T lymphocytes (CTLs) play a major role in eradicating cancer cells during immunotherapy, the cancer-associated immunosuppressive microenvironment often limits the success of such therapies. Therefore, the simultaneous induction of cancer-specific CTLs and reversal of t...

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Detalhes bibliográficos
Main Authors: Chang, Li-Sheng, Leng, Chih-Hsiang, Yeh, Yi-Chen, Wu, Chiao-Chieh, Chen, Hsin-Wei, Huang, Hai-Mei, Liu, Shih-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000133/
https://ncbi.nlm.nih.gov/pubmed/24642245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-60
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