Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice

Clinical complications associated with atherosclerotic plaques arise from luminal obstruction due to plaque growth or destabilization leading to rupture. Tumour necrosis factor ligand superfamily member 12 (TNFSF12) also known as TNF-related weak inducer of apoptosis (TWEAK) is a proinflammatory cyt...

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Autors principals: Sastre, Cristina, Fernández-Laso, Valvanera, Madrigal-Matute, Julio, Muñoz-García, Begoña, Moreno, Juan A, Pastor-Vargas, Carlos, Llamas-Granda, Patricia, Burkly, Linda C, Egido, Jesús, Martín-Ventura, Jose L, Blanco-Colio, Luis M
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons Ltd 2014
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000122/
https://ncbi.nlm.nih.gov/pubmed/24479820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12221
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