Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice

Clinical complications associated with atherosclerotic plaques arise from luminal obstruction due to plaque growth or destabilization leading to rupture. Tumour necrosis factor ligand superfamily member 12 (TNFSF12) also known as TNF-related weak inducer of apoptosis (TWEAK) is a proinflammatory cyt...

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Detalhes bibliográficos
Main Authors: Sastre, Cristina, Fernández-Laso, Valvanera, Madrigal-Matute, Julio, Muñoz-García, Begoña, Moreno, Juan A, Pastor-Vargas, Carlos, Llamas-Granda, Patricia, Burkly, Linda C, Egido, Jesús, Martín-Ventura, Jose L, Blanco-Colio, Luis M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000122/
https://ncbi.nlm.nih.gov/pubmed/24479820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12221
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